Methyl iodide → Ethyl 3-methylamino-4-cyclohexylphenylglyoxylate
반응식
[NH2:1][C:2]1[CH:3]=[C:4]([C:14](=[O:20])[C:15]([O:17][CH2:18][CH3:19])=[O:16])[CH:5]=[CH:6][C:7]=1[CH:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1.[CH3:21]I>N1C=CC=CC=1>[CH3:21][NH:1][C:2]1[CH:3]=[C:4]([C:14](=[O:20])[C:15]([O:17][CH2:18][CH3:19])=[O:16])[CH:5]=[CH:6][C:7]=1[CH:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1참가 물질
4
실험 절차
To a solution of 0.01 moles of ethyl 3-amino-4-cyclohexylphenylglyoxylate in 100 ml. of pyridine is added 0.1 moles of methyl iodide. The reaction mixture is stirred overnight at room temperature, filtered and concentrated. The residue is distilled to obtain ethyl 3-methylamino-4-cyclohexylphenylglyoxylate.
후처리
- filtrationfiltered
- concentrationconcentrated
- distillationThe residue is distilled
출처 및 근거
- ORD 기록
- ord-a2e369448a4f40eea2bd19b445797bbb
- 출처 데이터셋
- uspto-grants-1979_04
- 특허 번호
- US04150148
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