Dibenzylamine → n,n-Dibenzylformamide

HRID 26585

반응식

HRID 26585 반응식
[CH2:1]([NH:8][CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:16](OC(=O)C)(=[O:18])C>C(O)=O>[CH:16]([N:8]([CH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)[CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)=[O:18]

참가 물질

4

반응물 2

HCID 7656DibenzylamineHCID 7918Acetic Anhydride

생성물 1

HCID 221415n,n-Dibenzylformamide

시약·촉매·용매 1

HCID 284Formic Acid용매

실험 절차

To an ice-cold and vigorously stirred solution of dibenzylamine (918 g.) in 98% formic acid (105 ml.) is added dropwise, over 45 minutes, acetic anhydride (35 ml.). The resulting mixture is stirred for one hour at room temperature, then diluted with ice water (40 ml.) and kept overnight at 15° C. The solution is evaporated in vacuo to dryness and the residue extracted with ether. The ethereal solution is washed with water, dried over magnesium sulfate, filtered, and evaporated in vacuo to yield N-formyl-dibenzylamine (9.9 g.) as a white solid, m.p. 53°-54.5° C.

후처리

  1. waitkept overnight at 15° C
  2. customThe solution is evaporated in vacuo to dryness
  3. extractionthe residue extracted with ether
  4. washThe ethereal solution is washed with water
  5. dry with materialdried over magnesium sulfate
  6. filtrationfiltered
  7. customevaporated in vacuo

출처 및 근거

ORD 기록
ord-03a6fa7a7c6147029957a8734a984a23
출처 데이터셋
uspto-grants-1979_04
특허 번호
US04150223

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