Hydrochloric Acid → 4-[(2-Methylimidazo(1,2-a)pyridin 3-yl)methyl]benzonitrile hydrochloride
반응식
[CH3:1][C:2]1[N:3]=[C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][N:5]2[C:10]=1[CH2:11][C:12]1[CH:19]=[CH:18][C:15]([C:16]#[N:17])=[CH:14][CH:13]=1.C(OCC)(=O)C.[ClH:26]>C(O)C>[ClH:26].[CH3:1][C:2]1[N:3]=[C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][N:5]2[C:10]=1[CH2:11][C:12]1[CH:13]=[CH:14][C:15]([C:16]#[N:17])=[CH:18][CH:19]=1참가 물질
5
실험 절차
A mixture of 5 g of the product of Stage C, 80 ml of ethyl acetate and 3.5 ml of 6.6N hydrochloric acid in ethanol was ice-cooled, separated, washed with ethyl acetate and dried under reduced pressure at 80° C. to obtain 5 g of the expected product melting at 230° C.
후처리
- temperaturecooled
- customseparated
- washwashed with ethyl acetate
- customdried under reduced pressure at 80° C.
출처 및 근거
- ORD 기록
- ord-248af269534d45e8b3eb0bbc2a4a408f
- 출처 데이터셋
- uspto-grants-1997_07
- 특허 번호
- US05650414
반응 노트
불러오는 중…