Succinic anhydride → Digeranyl Succinate

HRID 266665

반응식

HRID 266665 반응식
[CH3:1][C:2](=[CH:4][CH2:5][CH2:6]/[C:7](=[CH:9]/[CH2:10][OH:11])/[CH3:8])[CH3:3].[OH:12][CH2:13]/[CH:14]=[C:15](/[CH3:22])\[CH2:16][CH2:17][CH:18]=[C:19]([CH3:21])[CH3:20].[C:23]1(=O)[O:28][C:26](=[O:27])[CH2:25][CH2:24]1>O>[C:23]([O:12][CH2:13]/[CH:14]=[C:15](/[CH2:16][CH2:17][CH:18]=[C:19]([CH3:21])[CH3:20])\[CH3:22])(=[O:28])[CH2:24][CH2:25][C:26]([O:11][CH2:10]/[CH:9]=[C:7](/[CH2:6][CH2:5][CH:4]=[C:2]([CH3:1])[CH3:3])\[CH3:8])=[O:27]

참가 물질

5

반응물 3

HCID 7922Succinic anhydrideHCID 637566GeraniolHCID 643820Nerol

생성물 1

HCID 22593555Digeranyl Succinate

시약·촉매·용매 1

HCID 962Water용매

실험 절차

Synthesis (c): A mixture of geraniol and nerol (approximately 70:30 by weight) in the amount of 94.86 g (0.615 mol) and succinic anhydride in the amount of 20.51 g (0.205 mol) are combined at room temperature. The mixture is heated to 140° C. for 6 h while water is removed using an argon sparge. After cooling to room temperature, the mixture is placed in a Kugelrohr oven and concentrated at 80°-85° C. for 5.5 h. Purity of the product is determined by thin layer chromatography and the structure confirmed by 13C and 1H NMR.

후처리

  1. customare combined at room temperature
  2. customis removed
  3. customsparge
  4. concentrationconcentrated at 80°-85° C. for 5.5 h

출처 및 근거

ORD 기록
ord-5995f2c1161e45688b92fedd26e95de3
출처 데이터셋
uspto-grants-1997_07
특허 번호
US05652205

연결된 노트

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