Anisole → N-(4-formyl-3-hydroxyphenyl)acetamide

반응식

[C:1]1([O:7]C)C=CC=CC=1.[C:9]([NH:12][C:13]1[CH:14]=[C:15]([OH:19])[CH:16]=[CH:17][CH:18]=1)(=[O:11])[CH3:10]>>[OH:19][C:15]1[CH:14]=[C:13]([NH:12][C:9](=[O:11])[CH3:10])[CH:18]=[CH:17][C:16]=1[CH:1]=[O:7]

참가 물질

반응물 2

HCID 7519Anisole

HCID 121243-Hydroxyacetanilide

생성물 1

HCID 12264699N-(4-formyl-3-hydroxyphenyl)acetamide

실험 절차

By operating according to Example 13, but using anisole as the solvent and a temperature of 100° C., and starting from 15.1 g of 3-acetylaminophenol, 9.0 g of a product (yield on the theoretical value=50%) having a melting point at 185°-186° C. were obtained.

후처리

customa temperature of 100° C.
customyield on the theoretical value=50%)
customat 185°-186° C.
customwere obtained

출처 및 근거

ORD 기록: ord-21f595ce2255497e8b72055a7472fa8b
출처 데이터셋: uspto-grants-1979_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04151201

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