Resorcinol → Ethyl 7-hydroxycoumarin-4-carboxylate

HRID 26697

반응식

HRID 26697 반응식
[C:1]1([CH:8]=[CH:7][CH:6]=[C:4]([OH:5])[CH:3]=1)[OH:2].[C:9](OCC)(=[O:18])[CH2:10][C:11]([C:13]([O:15][CH2:16][CH3:17])=[O:14])=O.[Na]>P(=O)(O)(O)O>[C:13]([C:11]1[C:8]2[C:1](=[CH:3][C:4]([OH:5])=[CH:6][CH:7]=2)[O:2][C:9](=[O:18])[CH:10]=1)([O:15][CH2:16][CH3:17])=[O:14]

참가 물질

4

반응물 2

HCID 5054ResorcinolHCID 57351814Diethyl 2-oxosuccinate,sodium salt

생성물 1

HCID 5702825Ethyl 7-hydroxycoumarin-4-carboxylate수율 80%

시약·촉매·용매 1

HCID 1004Phosphoric Acid용매

실험 절차

0.10 mole resorcinol and 0.12 mole sodium diethyl oxalacetate is heated to 80° C. for 1 hour in 60 ml concentrated phosphoric acid. 4-Carbethoxy-7-hydroxy-coumarin is thus obtained at an 80% yield in the form of a viscous oil.

출처 및 근거

ORD 기록
ord-74b6859fd148429f92bec5fdefd4dd3d
출처 데이터셋
uspto-grants-1979_04
특허 번호
US04151291

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