Potassium Hydroxide → 4-(Trifluoromethyl)-alpha-phenyl-o-toluidine

HRID 267414노트

반응식

HRID 267414 반응식
[NH2:1][C:2]1[CH:15]=[CH:14][C:13]([C:16]([F:19])([F:18])[F:17])=[CH:12][C:3]=1[C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)=O.[OH-].[K+]>C(O)COCCO>[F:17][C:16]([F:18])([F:19])[C:13]1[CH:12]=[C:3]([CH2:4][C:6]2[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=2)[C:2](=[CH:15][CH:14]=1)[NH2:1]

참가 물질

4

반응물 2

HCID 14797Potassium HydroxideHCID 13014169(2-Amino-5-(trifluoromethyl)phenyl)(phenyl)methanone

생성물 1

HCID 200619714-(Trifluoromethyl)-alpha-phenyl-o-toluidine

시약·촉매·용매 1

HCID 8117Diethylene Glycol용매

실험 절차

In the manner given in Preparation 11, 2-amino-5-(trifluoromethyl)benzophenone is refluxed with potassium hydroxide in diethylene glycol to give 4-(trifluoromethyl)-α-phenyl-o-toluidine.

출처 및 근거

ORD 기록
ord-553a518c8d1c4dfdad2db1b39df3b847
출처 데이터셋
uspto-grants-1976_03
특허 번호
US03941803

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