Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-Phenylhydroxylamine → 1-Trifluoromethyl-3-phenyl-3-hydroxyurea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-Phenylhydroxylamine | HCID 7518 | — |
| 반응물 | Pentane | HCID 8003 | — |
| 반응물 | Trifluoromethyl isocyanate | HCID 12494313 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 1-Trifluoromethyl-3-phenyl-3-hydroxyurea | HCID 21553678 | — |
반응 단계
A solution of trifluoromethyl isocyanate (11.1 grams, 0.1 mol) in diethyl ether (35 ml) is added dropwise, with stirring to a solution of N-phenyl hydroxylamine (10.9 grams; 0.1 mol) in ether (60 ml) at room temperature. Stirring is continued for a period of about 1 hour resulting in a precipitate. Pentane is added to the mixture to form additional precipitate. The precipitate is then recovered by filtration, is washed and dried to yield 1-trifluoromethyl-3-phenyl-3-hydroxyurea.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03944410 |
| 출처 데이터셋 | uspto-grants-1976_03 |
| ORD ID | ord-92f7c705668c44ad969cff59709360de |
| 출처 메모 | uspto-grants-1976_03 |