Hydrogen Peroxide → Cyclohexanone, trimethyl-

HRID 268116

반응식

HRID 268116 반응식
[OH:1]O.[OH-].[Na+].C[C:6]1[CH2:11][CH2:10][CH2:9][C:8]([CH3:13])([CH3:12])[C:7]=1[CH:14]=O.O>CO.S(=O)(=O)(O)O>[CH3:14][CH:7]1[CH2:6][CH2:11][CH2:10][C:9](=[O:1])[C:8]1([CH3:13])[CH3:12]

참가 물질

7

반응물 4

HCID 784Hydrogen PeroxideHCID 962WaterHCID 9895beta-CyclocitralHCID 14798Sodium Hydroxide

생성물 1

HCID 3016570Cyclohexanone, trimethyl-

시약·촉매·용매 2

HCID 1118Sulfuric Acid촉매HCID 887Methanol용매

실험 절차

110 ml of a solution of 30 % H2O2 followed by 28 ml of a 6N aqueous solution of NaOH were added dropwise, while stirring and within 45 minutes and 15 minutes, respectively, to a cooled solution (0°-5°) of 40 g of β-cyclocitral (0.26 mole) in 300 ml of methanol which had been acidified beforehand with 40 drops of concentrated sulphuric acid. The reaction mixture was then kept at room temperature for 3 days, while stirring. After having added water thereto, the said mixture was extracted three times with ether and the combined organic extracts were subjected to the usual treatments of washing (water), drying (MgSO4) and concentration. There were obtained 21.5 g of trimethyl-cyclohexanone by fractional distillation; b.p. 66°-69°/12 Torr (66 %).

후처리

  1. additionwere added dropwise
  2. waitThe reaction mixture was then kept at room temperature for 3 days
  3. stirringwhile stirring
  4. extractionthe said mixture was extracted three times with ether
  5. washof washing (water)
  6. customdrying
  7. concentration(MgSO4) and concentration

출처 및 근거

ORD 기록
ord-32828b8fe14547549316118173a6a1c0
출처 데이터셋
uspto-grants-1976_03
특허 번호
US03946078

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