1-Methylpiperazine → 4-{4-[3-(4-Methyl-piperazin-1-ylmethyl)-phenyl]-but-3-ynyl}-morpholine

HRID 268625

반응식

HRID 268625 반응식
[N:1]1([CH2:7][CH2:8][C:9]#[C:10][C:11]2[CH:12]=[C:13]([CH:16]=[CH:17][CH:18]=2)[CH:14]=O)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[CH3:19][N:20]1[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]1>>[CH3:19][N:20]1[CH2:25][CH2:24][N:23]([CH2:14][C:13]2[CH:12]=[C:11]([C:10]#[C:9][CH2:8][CH2:7][N:1]3[CH2:6][CH2:5][O:4][CH2:3][CH2:2]3)[CH:18]=[CH:17][CH:16]=2)[CH2:22][CH2:21]1

참가 물질

3

반응물 2

HCID 531671-MethylpiperazineHCID 224934723-(4-Morpholin-4-yl-but-1-ynyl)-benzaldehyde

생성물 1

HCID 103086564-{4-[3-(4-Methyl-piperazin-1-ylmethyl)-phenyl]-but-3-ynyl}-morpholine

실험 절차

May be prepared analogously to Example 15 using the product of Example 10 and 1-methylpiperazine.

출처 및 근거

ORD 기록
ord-e389281e307142d6b2ddc9c7435aaed4
출처 데이터셋
uspto-grants-2008_11
특허 번호
US07446104B2

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