2-Chloroethyl chloroformate → HCID 66783848, 화합물

HRID 270053노트

반응식

HRID 270053 반응식
Cl.ClC1C=C2C(=CC=1)OC1(CCNCC1)CC2.C([N:25]1[CH2:30][CH2:29][C:28]2([C:34]3[CH:35]=[CH:36][C:37]([F:39])=[CH:38][C:33]=3[CH2:32][O:31]2)[CH2:27][CH2:26]1)C1C=CC=CC=1.ClC(OCCCl)=O>>[F:39][C:37]1[CH:36]=[CH:35][C:34]2[C:28]3([O:31][CH2:32][C:33]=2[CH:38]=1)[CH2:27][CH2:26][NH:25][CH2:30][CH2:29]3

참가 물질

4

반응물 3

HCID 123052-Chloroethyl chloroformateHCID 68959958HCID 68959958, 화합물HCID 689620726-Chlorospiro[chroman-2,4'-piperidine] hydrochloride

생성물 1

HCID 66783848HCID 66783848, 화합물

실험 절차

This reaction was performed as described for (iii) above using 1′-benzyl-5-fluoro-3H-spiro[2-benzofuran-1,4′-piperidine] (145 mg, 0.487 mmol), chloroethyl chloroformate (0.07 mL) to give the titled compound.

출처 및 근거

ORD 기록
ord-251595ed730642049482f6fc83b4525c
출처 데이터셋
uspto-grants-2008_11
특허 번호
US07449475B2

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