Phosphoric Acid → 7-Benzoyl-2-oxindole

HRID 27364

반응식

HRID 27364 반응식
[C:1]([C:9]1[CH:10]=[CH:11][CH:12]=[C:13]2[C:17]=1[NH:16][CH:15]=[C:14]2Cl)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.P(=O)(O)(O)[OH:20]>>[C:1]([C:9]1[CH:10]=[CH:11][CH:12]=[C:13]2[C:17]=1[NH:16][C:15](=[O:20])[CH2:14]2)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 1004Phosphoric AcidHCID 12648508(3-Chloro-1H-indole-7-yl)phenylmethanone

생성물 1

HCID 1709837-Benzoyl-2-oxindole

실험 절차

The process as defined in claim 7 wherein 7-benzoyl-3-chloro-indole is hydrolyzed with phosphoric acid in a solvent at reflux temperature to produce 7-benzoylindolin-2-one.

후처리

  1. temperatureat reflux temperature

출처 및 근거

ORD 기록
ord-503b25ef239e43ff8f51d83788b37dda
출처 데이터셋
uspto-grants-1980_09
특허 번호
US04221716

연결된 노트

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