HCID 14614968, 화합물 → HCID 11024734, 화합물

HRID 273911노트

반응식

HRID 273911 반응식
[CH2:1]([O:8][C:9]([NH:11][CH:12]1[CH:25]2[CH:16]([C:17](=[O:27])[C:18]3[C:23]([C:24]2=[O:26])=[CH:22][CH:21]=[CH:20][CH:19]=3)[CH2:15][CH:14]=[CH:13]1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>[Cu]Cl.N1C=CC=CC=1>[CH2:1]([O:8][C:9]([NH:11][C:12]1[C:25]2[C:24](=[O:26])[C:23]3[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=3)[C:17](=[O:27])[C:16]=2[CH:15]=[CH:14][CH:13]=1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

4

반응물 1

HCID 14614968HCID 14614968, 화합물

생성물 1

HCID 11024734HCID 11024734, 화합물수율 88.2%

시약·촉매·용매 2

HCID 62652Cuprous chloride촉매HCID 1049Pyridine용매

실험 절차

0.47 g of 1-benzyloxycarbonylamino-1,4,4a,9a-tetrahydroanthraquinone, 6 mg of copper(I) chloride and 10 ml of pyridine were stirred at 25° C. for 30 hours under a gentle stream of air and the solution was then concentrated in vacuo. The residue was taken up in chloroform, the solution was extracted with 2N hydrochloric acid and the organic phase was concentrated in vacuo. 0.41 g of 1-benzyloxycarbonylaminoanthraquinone (86% pure; 76% of theory) was obtained.

후처리

  1. concentrationthe solution was then concentrated in vacuo
  2. extractionthe solution was extracted with 2N hydrochloric acid
  3. concentrationthe organic phase was concentrated in vacuo

출처 및 근거

ORD 기록
ord-d963fcfe3a7549d4b179f25a147e5fff
출처 데이터셋
uspto-grants-1995_02
특허 번호
US05387704

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