Sodium Hydroxide → 1-Aminoanthraquinone

HRID 273912노트

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HRID 273912 반응식
C(OC([NH:11][C:12]1[C:25]2[C:24](=[O:26])[C:23]3[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=3)[C:17](=[O:27])[C:16]=2[CH:15]=[CH:14][CH:13]=1)=O)C1C=CC=CC=1.[OH-].[Na+]>C(O)C>[NH2:11][C:12]1[C:25]2[C:24](=[O:26])[C:23]3[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=3)[C:17](=[O:27])[C:16]=2[CH:15]=[CH:14][CH:13]=1

참가 물질

4

반응물 2

HCID 14798Sodium HydroxideHCID 11024734HCID 11024734, 화합물

생성물 1

HCID 67101-Aminoanthraquinone수율 96.1%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

0.50 g of 1-benzyloxycarbonylaminoanthraquinone, 25 ml of ethanol and 25 ml of 50% strength aqueous sodium hydroxide solution were heated under reflux for 6 hours and the solution was then concentrated in vacuo. The residue was taken up in chloroform/water, the phases were separated and the organic phase was washed twice with water. The organic phase was concentrated in vacuo and 0.30 g of 1-aminoanthraquinone (99% pure; 95% of theory) was obtained.

후처리

  1. temperatureunder reflux for 6 hours
  2. concentrationthe solution was then concentrated in vacuo
  3. customthe phases were separated
  4. washthe organic phase was washed twice with water
  5. concentrationThe organic phase was concentrated in vacuo

출처 및 근거

ORD 기록
ord-49308a0a18cb40239263b61309c0a178
출처 데이터셋
uspto-grants-1995_02
특허 번호
US05387704

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