Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride → alpha-(3,4-Dimethoxyphenyl)-3,4-dihydro-6,7-dimethoxy-gamma-methyl-alpha-[(4-methylphenyl)thio]-2(1H)-isoquino linepentanenitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride | HCID 6456035 | — |
| 반응물 | alpha-(3-Chloro-2-methylpropyl)-3,4-dimethoxy-alpha-[(4-methylphenyl)thio]benzeneacetonitrile | HCID 19042099 | — |
| 생성물 | alpha-(3,4-Dimethoxyphenyl)-3,4-dihydro-6,7-dimethoxy-gamma-methyl-alpha-[(4-methylphenyl)thio]-2(1H)-isoquino linepentanenitrile | HCID 20094567 | 17,563.4% |
반응 단계
The procedure of Example 2 is repeated using 4.0 g of α-(3-chloro-2-methylpropyl)-3,4-dimethoxy-α-[(4-methylphenyl)thio]benzeneacetonitrile and 3.5 g of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride. This affords 0,985 g of the desired product as a yellow foam.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05387685 |
| 출처 데이터셋 | uspto-grants-1995_02 |
| ORD ID | ord-77e0ce66614b4cff85a6c75c9625f1b0 |
| 출처 메모 | uspto-grants-1995_02 |