Trimethyl borate → 2-Propynyl-6-fluoropyridin-5-ylboric acid
반응식
[C:1]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([F:10])[N:5]=1)#[C:2][CH3:3].[Li+].CC([N-]C(C)C)C.[B:19]([O:24]C)([O:22]C)[O:20]C>>[C:1]([C:4]1[CH:9]=[CH:8][C:7]([O:20][B:19]([OH:24])[OH:22])=[C:6]([F:10])[N:5]=1)#[C:2][CH3:3]참가 물질
4
실험 절차
0.05 mol of 10A, 0.08 mol of LDA and 0.08 mol of trimethyl borate are reacted with one another analogously to Example 1B. Aqueous work-up gives the unpurified product, which is processed further as in 10C.
출처 및 근거
- ORD 기록
- ord-a3739a3bb60d49919ae412b401376986
- 출처 데이터셋
- uspto-grants-1995_02
- 특허 번호
- US05389291
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