Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Acid → 4-Methyl-2-nitrobenzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | 2-Nitro-4-toluonitrile | HCID 96235 | — |
| 용매 | Sulfuric Acid | HCID 1118 | — |
| 생성물 | 4-Methyl-2-nitrobenzoic acid | HCID 255027 | — |
반응 단계
A mixed solution of 2-nitro-4-methylbenzonitrile (15.8 g) in a mixture of 65% sulfuric acid and acetic acid (150 ml) was heated under reflux for 17 hours. After concentration, the residue was poured into ice-water and extracted with ethyl acetate. The extract was washed with water, dried and concentrated to dryness. Recrystallization of crystals from ether-hexane afforded colorless crystals (16.5 g, 94%), m.p. 156°-157° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05389641 |
| 출처 데이터셋 | uspto-grants-1995_02 |
| ORD ID | ord-3db63667ac724b178f81ecd389f3541d |
| 출처 메모 | uspto-grants-1995_02 |