6-Nitro-o-anisidine → 3-Methoxybenzene-1,2-diamine

HRID 275787

반응식

HRID 275787 반응식
[NH2:1][C:2]1[C:7]([N+:8]([O-])=O)=[CH:6][CH:5]=[CH:4][C:3]=1[O:11][CH3:12]>C(OCC)(=O)C.[Pd]>[NH2:1][C:2]1[C:7]([NH2:8])=[CH:6][CH:5]=[CH:4][C:3]=1[O:11][CH3:12]

참가 물질

4

반응물 1

HCID 854916-Nitro-o-anisidine

생성물 1

HCID 1842683-Methoxybenzene-1,2-diamine수율 101.9%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 8857Ethyl Acetate용매

실험 절차

2-Amino-3-nitroanisole (4.3 g) was hydrogenated in ethyl acetate (200 ml) using catalytic 10% palladium on charcoal under an atmosphere of hydrogen at ambient temperature. Once complete the reaction mixture was filtered through Celite and the filtrate evaporated in vacuo to afford the title compound as a brown liquid (3.60 g).

후처리

  1. customat ambient temperature
  2. filtrationwas filtered through Celite
  3. customthe filtrate evaporated in vacuo

출처 및 근거

ORD 기록
ord-1931361c855c4e49b5bf142cad92b2bd
출처 데이터셋
uspto-grants-2002_03
특허 번호
US06353010B1

연결된 노트

불러오는 중…