1-Bromopropane → 7-Methoxy-3-propyl-2-trifluoromethylbenzimidazole

HRID 275793

반응식

HRID 275793 반응식
[CH3:1][O:2][C:3]1[C:11]2[NH:10][C:9]([C:12]([F:15])([F:14])[F:13])=[N:8][C:7]=2[CH:6]=[CH:5][CH:4]=1.[CH2:16](Br)[CH2:17][CH3:18]>>[CH3:1][O:2][C:3]1[C:11]2[N:10]=[C:9]([C:12]([F:15])([F:13])[F:14])[N:8]([CH2:16][CH2:17][CH3:18])[C:7]=2[CH:6]=[CH:5][CH:4]=1

참가 물질

3

반응물 2

HCID 78401-BromopropaneHCID 178488964HCID 178488964, 화합물

생성물 1

HCID 183166377-Methoxy-3-propyl-2-trifluoromethylbenzimidazole

실험 절차

Prepared from 4-methoxy-2-trifluoromethylbenzimidazole (2.4 g) and propyl bromide (3.02 ml). Purification by flash chromatography on silica eluting with 15% ethyl acetate in hexane gave the title compound as a white solid (2.03 g).

후처리

  1. customPurification by flash chromatography on silica eluting with 15% ethyl acetate in hexane

출처 및 근거

ORD 기록
ord-3768b69c0a5644d48eb12c0816af51a4
출처 데이터셋
uspto-grants-2002_03
특허 번호
US06353010B1

연결된 노트

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