Water → 2-Ethylbenzo[d]oxazol-4-ol

HRID 275797

반응식

HRID 275797 반응식
Cl.[NH2:2][C:3]1[C:9]([OH:10])=[CH:8][CH:7]=[CH:6][C:4]=1[OH:5].C(O[C:14](OCC)(OCC)[CH2:15][CH3:16])C.O>C(O)C>[CH2:15]([C:16]1[O:5][C:4]2[CH:6]=[CH:7][CH:8]=[C:9]([OH:10])[C:3]=2[N:2]=1)[CH3:14]

참가 물질

5

반응물 3

HCID 962WaterHCID 66995Ethyl orthopropionateHCID 4592471,3-Benzenediol, 2-amino-, hydrochloride (1:1)

생성물 1

HCID 156656802-Ethylbenzo[d]oxazol-4-ol

시약·촉매·용매 1

HCID 702Ethanol용매

반응 조건

온도
150 °C

실험 절차

A mixture of 2-aminoresorcinol hydrochloride (5.0 g) and triethylorthopropionate (13.7 ml) was heated to 150° C. for 2 h before being poured into a mixture of water (140 ml) and ethanol (35 ml). The mixture was stirred vigorously for 30 minutes at room temperature. The resulting precipitate was removed by filtration and dried to give the title compound as a beige solid (4.11 g).

후처리

  1. customThe resulting precipitate was removed by filtration
  2. customdried

출처 및 근거

ORD 기록
ord-431cdd863f2841b39b43c21f7b1cdf97
출처 데이터셋
uspto-grants-2002_03
특허 번호
US06353010B1

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