Hydrogen Peroxide → 3-Phenoxyphenylacetamide
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[O:1]([C:8]1[CH:9]=[C:10]([CH2:14][C:15]#[N:16])[CH:11]=[CH:12][CH:13]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(=O)([O-])[O-:18].[K+].[K+].OO>CS(C)=O>[O:1]([C:8]1[CH:9]=[C:10]([CH2:14][C:15]([NH2:16])=[O:18])[CH:11]=[CH:12][CH:13]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1참가 물질
5
실험 절차
3-Phenoxyphenylacetonitrile (1.0 g; 4.8 mmol) was dissolved in DMSO (3 mL) and cooled in an ice-water bath. Potassium carbonate (0.2 g; 1.5 mmol) was added, followed by dropwise addition of 1.0 mL of 30% hydrogen peroxide. The bath was removed, and the mixture allowed to warm to room temperature while stirring for 40 min. Water was added, and the product isolated as a white crystalline solid by filtration, and washed with fresh water. mp 115-117° C.
후처리
- temperaturecooled in an ice-water bath
- customThe bath was removed
- additionWater was added
- customthe product isolated as a white crystalline solid by filtration
- washwashed with fresh water
출처 및 근거
- ORD 기록
- ord-dbb83390cd10482e992f71a7aae7ee00
- 출처 데이터셋
- uspto-grants-2002_03
- 특허 번호
- US06353128B1
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