Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Allyl bromide → 3-Chloromethyl-benzoic acid allyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Allyl bromide | HCID 7841 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 3-(Chloromethyl)benzoic acid | HCID 241752 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 3-Chloromethyl-benzoic acid allyl ester | HCID 11424370 | — |
반응 단계
A solution of 3-(chloromethyl)-benzoic acid (50.0 g, 0.293 mol), potassium carbonate (48.61 g, 0.352 mol) and allyl bromide (50.7 mL, 0.586 mol) in acetone (500 mL) is refluxed for 2 hours, after which time the solution was cooled to room temp. and filtered through celite. The filtrate is evaporated and the residue chromatographed (silica, 5% EtOAc/hexane) to yield allyl 3-(chloromethyl)-benzoate as a clear oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06353017B1 |
| 출처 데이터셋 | uspto-grants-2002_03 |
| ORD ID | ord-cf5788fce5884aba8062303175a062fa |
| 출처 메모 | uspto-grants-2002_03 |