5-Methylthiophene-2-carbohydrazide → 5-Methyl-thiophen-2-carboxylic acid (1-amino-2-benzenesulfonyl-ethylidene)-hydrazide

HRID 277030

반응식

HRID 277030 반응식
C(O[C:4](=[NH:15])[CH2:5][S:6]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)(=[O:8])=[O:7])C.[CH3:16][C:17]1[S:21][C:20]([C:22]([NH:24][NH2:25])=[O:23])=[CH:19][CH:18]=1>C(Cl)(Cl)Cl>[NH2:15][C:4](=[N:25][NH:24][C:22]([C:20]1[S:21][C:17]([CH3:16])=[CH:18][CH:19]=1)=[O:23])[CH2:5][S:6]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)(=[O:8])=[O:7]

참가 물질

4

반응물 2

HCID 27600855-Methylthiophene-2-carbohydrazideHCID 700894422-(Phenylsulfonyl)-ethanimidic acid ethyl ester

생성물 1

HCID 700905765-Methyl-thiophen-2-carboxylic acid (1-amino-2-benzenesulfonyl-ethylidene)-hydrazide수율 91.2%

시약·촉매·용매 1

HCID 6212Chloroform용매

실험 절차

1.75 g (0.0077 Mol) of 2-(phenylsulfonyl)-ethanimidic acid ethyl ester was stirred together with 1.2 g (0.0077 mol) 5-methyl-thiophen-2-carboxylic acid hydrazide in 14 ml chloroform for 24 hours at 50° C. The resulting precipitate was filtered off and dried. 2.37 g of 5-methyl-thiophen-2-carboxylic acid (1-amino-2-benzenesulfonyl-ethylidene)-hydrazide was obtained as off-white crystals. Mp.: 222° C. (dec.).

후처리

  1. filtrationThe resulting precipitate was filtered off
  2. customdried

출처 및 근거

ORD 기록
ord-320543ae4d58441c90f95b881d746d71
출처 데이터셋
uspto-grants-2002_03
특허 번호
US06355653B1

연결된 노트

불러오는 중…