Hydrochloric Acid → 1-[2-(4-Chlorophenyl)ethynesulfonyl]piperazine hydrochloride

HRID 278579노트

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HRID 278579 반응식
C(OC([N:8]1[CH2:13][CH2:12][N:11]([S:14]([C:17]#[C:18][C:19]2[CH:24]=[CH:23][C:22]([Cl:25])=[CH:21][CH:20]=2)(=[O:16])=[O:15])[CH2:10][CH2:9]1)=O)(C)(C)C.Cl>C(OCC)(=O)C>[ClH:25].[Cl:25][C:22]1[CH:23]=[CH:24][C:19]([C:18]#[C:17][S:14]([N:11]2[CH2:10][CH2:9][NH:8][CH2:13][CH2:12]2)(=[O:16])=[O:15])=[CH:20][CH:21]=1

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 226280621-(Tert-butoxycarbonyl)-4-[2-(4-chlorophenyl)ethynesulfonyl]piperazine

생성물 1

HCID 226280021-[2-(4-Chlorophenyl)ethynesulfonyl]piperazine hydrochloride수율 182.1%

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

실험 절차

1-(tert-Butoxycarbonyl)-4-[2-(4-chlorophenyl)ethynesulfonyl]piperazine (500 mg) was treated with 4N hydrochloric acid in ethyl acetate to give a colorless solid of the title compound (380 mg).

출처 및 근거

ORD 기록
ord-0ea6e2abc8d243388cf9f0006b4d0563
출처 데이터셋
uspto-grants-2002_03
특허 번호
US06359134B1

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