Benzoyl fluoride, 4-(trifluoromethoxy)- → 2-(p-TRIFLUOROMETHOXYPHENYL)-1H-PERIMIDINE HYDROFLUORIDE

HRID 27885

반응식

HRID 27885 반응식
[NH2:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][C:10]=2[NH2:12])[CH:5]=[CH:4][CH:3]=1.[F:13][C:14]([F:26])([F:25])[O:15][C:16]1[CH:24]=[CH:23][C:19]([C:20](F)=O)=[CH:18][CH:17]=1>C1(C)C=CC=CC=1>[FH:13].[F:13][C:14]([F:25])([F:26])[O:15][C:16]1[CH:17]=[CH:18][C:19]([C:20]2[NH:1][C:2]3[CH:3]=[CH:4][CH:5]=[C:6]4[C:11]=3[C:10]([N:12]=2)=[CH:9][CH:8]=[CH:7]4)=[CH:23][CH:24]=1

참가 물질

4

반응물 2

HCID 67612Benzoyl fluoride, 4-(trifluoromethoxy)-HCID 680671,8-Diaminonaphthalene

생성물 1

HCID 129454392-(p-TRIFLUOROMETHOXYPHENYL)-1H-PERIMIDINE HYDROFLUORIDE

시약·촉매·용매 1

HCID 1140Toluene용매2회

실험 절차

1,8-Diaminonaphthalene (1.52 grams; 0.0096 mole) was dissolved in 25 ml. of toluene, then decanted. p-Trifluoromethoxybenzoyl fluoride (2.0 grams; 0.0096 mole) was dissolved in 25 ml. of toluene. Both solutions were added simultaneously to 25 ml. of toluene. After the reaction mixture had been stirred for approximately 4 hours, TLC indicated that the reaction was complete.

후처리

  1. customof toluene, then decanted
  2. additionBoth solutions were added simultaneously to 25 ml

출처 및 근거

ORD 기록
ord-ef9f817d260c40a48ed57129ebeb83cc
출처 데이터셋
uspto-grants-1980_09
특허 번호
US04224326

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