Hydrochloric Acid → 2,3-Dichloro-5-(trichloromethyl)pyridine

HRID 279738

반응식

HRID 279738 반응식
Br[C:2]1[C:3]([Cl:9])=[N:4][CH:5]=[C:6](C)[CH:7]=1.[ClH:10].ClCl.[C:13]([Cl:17])(Cl)([Cl:15])[Cl:14]>>[Cl:9][C:3]1[C:2]([Cl:10])=[CH:7][C:6]([C:13]([Cl:17])([Cl:15])[Cl:14])=[CH:5][N:4]=1

참가 물질

5

반응물 4

HCID 313Hydrochloric AcidHCID 5943Carbon TetrachlorideHCID 24526ChlorineHCID 2854373-Bromo-2-chloro-5-methylpyridine

생성물 1

HCID 946472,3-Dichloro-5-(trichloromethyl)pyridine

실험 절차

The product from (b) (64 g) in dry carbon tetrachloride (650 ml) was treated with dry hydrogen chloride. The precipitate was broken up and the suspension heated under reflux while dry chlorine was bubbled into the mixture, with illumination from an ultra-violet light source. After 41/2 hours, the mixture was cooled, filtered, and the filtrate evaporated to give the required 2,3-dichloro-5-trichloromethylpyridine. The mass spectrum was consistent with the structure assigned to this compound.

후처리

  1. temperaturethe suspension heated
  2. customwas bubbled into the mixture, with illumination from an ultra-violet light source
  3. temperatureAfter 41/2 hours, the mixture was cooled
  4. filtrationfiltered
  5. customthe filtrate evaporated

출처 및 근거

ORD 기록
ord-2eba13a864c74495ba0de00f3e62458a
출처 데이터셋
uspto-grants-1986_05
특허 번호
US04586953

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