Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → HCID 13478097, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 2-Chloroquinazoline | HCID 74054 | — |
| 반응물 | 1-[3-(4-Fluorophenoxy)propyl]piperazine | HCID 1873396 | — |
| 용매 | Isopropanol | HCID 3776 | — |
| 생성물 | HCID 13478097 | HCID 13478097 | — |
반응 단계
2.5 g 2-Chloro-quinazoline, 3.8 g 1-[3-(4-fluorophenoxy)propyl]piperazine and 2.5 ml triethylamine in 15 ml isopropanol are stirred under reflux for 5 hours. The solvent is then evaporated in vacuo and the residue partitioned between water and methylene chloride. The organic phase is dried and evaporated. The residue is recrystallized from ethanol to yield the title compound, m.p. 126°-128° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04588725 |
| 출처 데이터셋 | uspto-grants-1986_05 |
| ORD ID | ord-87f2de8023f14f53ac1b7ff2295fa747 |
| 출처 메모 | uspto-grants-1986_05 |