Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-(3-Chlorophenyl)-2-oxoacetaldehyde → N-(3-(4-Methylphenyl)-1,1-dimethylpropyl)-2-hydroxy-2-(3-chlorophenyl)ethanamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-(3-Chlorophenyl)-2-oxoacetaldehyde | HCID 12463893 | — |
| 반응물 | 2-Methyl-4-(4-methylphenyl)butan-2-amine | HCID 23322167 | — |
| 생성물 | N-(3-(4-Methylphenyl)-1,1-dimethylpropyl)-2-hydroxy-2-(3-chlorophenyl)ethanamine | HCID 23322177 | — |
반응 단계
The title compound was prepared in the manner described in Example 9 using 3-chlorophenylglyoxal and 3-(4-methylphenyl)-1,1-dimethylpropanamine. The chromatographed material was recrystallized from cyclohexane to give the title compound m.p. 136. τ(CDCL3 +d6DMSO) 8.9 (6H, s), 8.2-8.4 (2H, m), 7.7 (3H, s), 7.0-7.6 (4H, m), 5.35 (1H, dd), 2.9 (4H, s), 2.5-2.7 (5H, m).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04588749 |
| 출처 데이터셋 | uspto-grants-1986_05 |
| ORD ID | ord-2d8e56e2bf444a0ab85fdddb57b92ca8 |
| 출처 메모 | uspto-grants-1986_05 |