Ammonia → HCID 20195198, 화합물

HRID 280444노트

반응식

HRID 280444 반응식
[Br:1][C:2]1[CH:3]=[C:4]([S:14](Cl)(=[O:16])=[O:15])[C:5]2[O:10][S:9](=[O:12])(=[O:11])[CH:8]=[CH:7][C:6]=2[CH:13]=1.[NH3:18].Cl>O1CCCC1>[Br:1][C:2]1[CH:3]=[C:4]([S:14](=[O:16])(=[O:15])[NH2:18])[C:5]2[O:10][S:9](=[O:12])(=[O:11])[CH:8]=[CH:7][C:6]=2[CH:13]=1

참가 물질

5

반응물 3

HCID 222AmmoniaHCID 313Hydrochloric AcidHCID 20195206HCID 20195206, 화합물

생성물 1

HCID 20195198HCID 20195198, 화합물

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

The crystalline product obtained in (c) is dissolved in as small an amount of tetrahydrofuran as possible and the solution is added dropwise to 20 ml of 25% aqueous ammonia solution. After the reaction mixture has been stirred for 30 minutes it is poured into a mixture of ice and 10% hydrochloric acid. Extraction with ether yields 0.3 g of 6-bromo-8-sulfamoyl-2,2-dioxo-1,2-benzoxathiine of m.p. 224°-228° C. (decomposition with black colouration).

후처리

  1. extractionExtraction with ether

출처 및 근거

ORD 기록
ord-037a6fadecc54d7a9bb5d1cddbc7b7eb
출처 데이터셋
uspto-grants-1986_05
특허 번호
US04589911

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