Hydrochloric Acid → HCID 53739261, 화합물

HRID 280614노트

반응식

HRID 280614 반응식
[CH3:1][C:2]1[S:6][C:5]2[C:7]([C:11]([OH:13])=[O:12])=[CH:8][CH:9]=[CH:10][C:4]=2[CH:3]=1.Cl.[CH3:15]O>>[CH3:15][O:12][C:11]([C:7]1[C:5]2[S:6][C:2]([CH3:1])=[CH:3][C:4]=2[CH:10]=[CH:9][CH:8]=1)=[O:13]

참가 물질

4

반응물 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 126239032-Methyl-1-benzothiophene-7-carboxylic acid

생성물 1

HCID 53739261HCID 53739261, 화합물

실험 절차

A solution of 2-methylbenzo[b]thiophene-7-carboxylic acid (5.1 g) in methanol (100 ml) was saturated with hydrogen chloride and then heated under reflux for 18 hours. The solution was evaporated and the residue was dissolved in ether. The ether solution was washed with sodium carbonate solution and dried (Na2SO4). Evaporation of the ether gave 2-methylbenzo[b]thiophene-7-carboxylic acid methyl ester (4.7 g), m.p. 48°-49°.

후처리

  1. temperatureheated
  2. temperatureunder reflux for 18 hours
  3. customThe solution was evaporated
  4. dissolutionthe residue was dissolved in ether
  5. washThe ether solution was washed with sodium carbonate solution
  6. dry with materialdried (Na2SO4)
  7. customEvaporation of the ether

출처 및 근거

ORD 기록
ord-6f87be024b13420eb8893aea4f40d0c7
출처 데이터셋
uspto-grants-1986_05
특허 번호
US04590200

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