2-Amino-4-methoxy-6-methyl-1,3,5-triazine → Metsulfuron-methyl

HRID 280808

반응식

HRID 280808 반응식
[NH2:1][C:2]1[N:7]=[C:6]([O:8][CH3:9])[N:5]=[C:4]([CH3:10])[N:3]=1.[CH3:11][O:12][C:13]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[S:21]([N:24]=[C:25]=[O:26])(=[O:23])=[O:22])=[O:14]>C(Cl)Cl>[CH3:9][O:8][C:6]1[N:5]=[C:4]([CH3:10])[N:3]=[C:2]([NH:1][C:25]([NH:24][S:21]([C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=2[C:13]([O:12][CH3:11])=[O:14])(=[O:23])=[O:22])=[O:26])[N:7]=1

참가 물질

4

반응물 2

HCID 154662-Amino-4-methoxy-6-methyl-1,3,5-triazineHCID 156281Benzoic acid, 2-(isocyanatosulfonyl)-, methyl ester

생성물 1

HCID 52999Metsulfuron-methyl

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

To an anhydrous suspension of 1.4 g of 2-amino-4-methoxy-6-methyl-1,3,5-triazine in 25 ml of methylene chloride was added with stirring at ambient temperature and pressure 2.4 g of 2-methoxycarbonylbenzenesulfonylisocyanate. The mixture was thereafter stirred for 16 hours and filtered. The filtrate was evaporated to dryness, the residue was triturated with butyl chloride and the product removed by filtration. The product thus obtained melted at 165°, and had absorption peaks in the infrared at 1550, 1600, 1680 and 1700 cm-1 and in the NMR spectrum at 2.5, 3.65, 4.0 with an aromatic multiplet at 7.2-8 ppm.

후처리

  1. additionwas added
  2. stirringThe mixture was thereafter stirred for 16 hours
  3. filtrationfiltered
  4. customThe filtrate was evaporated to dryness
  5. customthe residue was triturated with butyl chloride
  6. customthe product removed by filtration
  7. customabsorption peaks in the

출처 및 근거

ORD 기록
ord-3834d153aec0412a9959e1a379c2f6f7
출처 데이터셋
uspto-grants-1986_05
특허 번호
US04591378

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