Sodium Hydroxide → HCID 178418482, 화합물
반응식
[O:1]=[C:2]([CH3:7])[CH2:3][C:4]([NH2:6])=[O:5].[OH-].[Na+].[Cl-].[C:11]1([N+:17]#[N:18])[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>O>[C:11]1([NH:17][N:18]=[C:3]([C:2](=[O:1])[CH3:7])[C:4]([NH2:6])=[O:5])[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1참가 물질
5
실험 절차
5.0 g (0.049 mol) of 3-oxobutyramide, a solution of 6.9 g (0.171 mol) of NaOH in 75 ml of water and 0.051 mol of phenyldiazonium chloride were treated as described in preparation 8. The crude reaction mixture was purified by chromatography on silica gel(EtOAc) obtaining 3 g of the title compound which was used as such in the subsequent step. M.p.=146°-147° C.
후처리
- customas described in preparation 8
- customThe crude reaction mixture
- customwas purified by chromatography on silica gel(EtOAc) obtaining 3 g of the title compound which
출처 및 근거
- ORD 기록
- ord-fa496a7ce126439c8a04c703ffcedc08
- 출처 데이터셋
- uspto-grants-1998_03
- 특허 번호
- US05731322
반응 노트
불러오는 중…