N-bromobutanimide → HCID 178526566, 화합물

HRID 28915

반응식

HRID 28915 반응식
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]2[NH:14][N:13]=[CH:12][CH:11]=2)=[CH:6][CH:5]=1)([O-:3])=[O:2].[Br:15]N1C(=O)CCC1=O>CN(C)C=O>[Br:15][C:11]1[C:10]([C:7]2[CH:6]=[CH:5][C:4]([N+:1]([O-:3])=[O:2])=[CH:9][CH:8]=2)=[N:14][NH:13][CH:12]=1

참가 물질

4

반응물 2

HCID 67184N-bromobutanimideHCID 27370713-(4-Nitrophenyl)-1H-pyrazole

생성물 1

HCID 178526566HCID 178526566, 화합물수율 90%

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

A solution of 5-(4-nitrophenyl)-1H-pyrazole (595 mmol) in N,N-dimethylformamide (1000 mL) was treated with N-bromosuccinimide (654 mmol). The reaction stirred for 30 min at room temperature and was poured into ice-water (1000 mL). Product precipitated out of solution, was filtered, washed with water (4×500 mL) and dried to provide the title product as an off-white powder (90%). ESMS [M+H]+: 269.2

후처리

  1. customProduct precipitated out of solution
  2. filtrationwas filtered
  3. washwashed with water (4×500 mL)
  4. customdried

출처 및 근거

ORD 기록
ord-83f86aed998c4c9a9d7392ced2dbfd50
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07419988B2

연결된 노트

불러오는 중…