2-Phenylisobutyric acid → 2-Methyl-2-phenylpropanoyl chloride

HRID 29517

반응식

HRID 29517 반응식
[CH3:1][C:2]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)([CH3:6])[C:3](O)=[O:4].C(Cl)(=O)C([Cl:16])=O>ClCCl>[CH3:1][C:2]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)([CH3:6])[C:3]([Cl:16])=[O:4]

참가 물질

4

반응물 2

HCID 132222-Phenylisobutyric acidHCID 65578Oxalyl chloride

생성물 1

HCID 123690862-Methyl-2-phenylpropanoyl chloride

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

A solution of 2-Methyl-2-phenylpropionic acid (10 mmol, 1.0 eq.) and oxalyl chloride (40 mmol, 4.0 eq.) in dichloromethane (30 mL) was stirred at room temperature for 18 h. The mixture was concentrated in vacuo to afford the title compound as a yellow oil.

후처리

  1. concentrationThe mixture was concentrated in vacuo

출처 및 근거

ORD 기록
ord-b388f55835f0450eb8040b6671d8a7a3
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07420055B2

연결된 노트

불러오는 중…