2-Phenylisobutyric acid → 2-Methyl-2-phenylpropanoyl chloride
반응식
[CH3:1][C:2]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)([CH3:6])[C:3](O)=[O:4].C(Cl)(=O)C([Cl:16])=O>ClCCl>[CH3:1][C:2]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)([CH3:6])[C:3]([Cl:16])=[O:4]참가 물질
4
실험 절차
A solution of 2-Methyl-2-phenylpropionic acid (10 mmol, 1.0 eq.) and oxalyl chloride (40 mmol, 4.0 eq.) in dichloromethane (30 mL) was stirred at room temperature for 18 h. The mixture was concentrated in vacuo to afford the title compound as a yellow oil.
후처리
- concentrationThe mixture was concentrated in vacuo
출처 및 근거
- ORD 기록
- ord-b388f55835f0450eb8040b6671d8a7a3
- 출처 데이터셋
- uspto-grants-2008_09
- 특허 번호
- US07420055B2
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