4-Fluorobenzohydrazide → 4-Fluoro-benzoic acid-(1-imino-ethyl)-hydrazide

반응식

Cl.[C:2](=[NH:7])(OCC)[CH3:3].[F:8][C:9]1[CH:18]=[CH:17][C:12]([C:13]([NH:15][NH2:16])=[O:14])=[CH:11][CH:10]=1>>[NH:7]=[C:2]([N:15]([C:13](=[O:14])[C:12]1[CH:17]=[CH:18][C:9]([F:8])=[CH:10][CH:11]=1)[NH2:16])[CH3:3]

참가 물질

반응물 2

HCID 99724-Fluorobenzohydrazide

HCID 2724290Ethanimidic acid, ethyl ester, hydrochloride (1:1)

생성물 1

HCID 684925634-Fluoro-benzoic acid-(1-imino-ethyl)-hydrazide

실험 절차

Prepared from 7.2 g (58 mmol) ethyl acetimidate hydrochloride and 5.00 g (32 mmol) 4-fluoro-benzoic acid hydrazide analogously to the method described for intermediate product la). Yield: 5.78 g (91%); mass spectroscopy [M+H]+=196.

출처 및 근거

ORD 기록: ord-b41695718a664a768a837ad4a3875418
출처 데이터셋: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07423036B2

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