4-Methoxybenzohydrazide → HCID 178491626, 화합물

HRID 29812

반응식

HRID 29812 반응식
[Na].Cl.[C:3](=[NH:8])(OCC)[CH3:4].[CH3:9][O:10][C:11]1[CH:20]=[CH:19][C:14]([C:15]([NH:17][NH2:18])=[O:16])=[CH:13][CH:12]=1>C(O)C>[NH:8]=[C:3]([NH:18][NH:17][C:15](=[O:16])[C:14]1[CH:13]=[CH:12][C:11]([O:10][CH3:9])=[CH:20][CH:19]=1)[CH3:4]

참가 물질

5

반응물 3

HCID 767924-MethoxybenzohydrazideHCID 2724290Ethanimidic acid, ethyl ester, hydrochloride (1:1)HCID 5360545Sodium

생성물 1

HCID 178491626HCID 178491626, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매2회

실험 절차

4.6 g (0.20 mol) sodium in 200 mL ethanol are combined at ambient temperature with a solution of 25 g (0.20 mol) ethyl acetimidate hydrochloride in 200 mL ethanol. The sodium chloride precipitated is suction filtered and 33.2 g (0.20 mol) 4-methoxybenzoic acid hydrazide are added to the filtrate. The reaction mixture is stirred overnight at ambient temperature and then cooled. The precipitate formed is separated off and washed with ethanol and diethyl ether. Yield: 33.6 g (81%); melting range=179-181° C.

후처리

  1. customThe sodium chloride precipitated
  2. filtrationfiltered
  3. temperaturecooled
  4. customThe precipitate formed
  5. customis separated off
  6. washwashed with ethanol and diethyl ether

출처 및 근거

ORD 기록
ord-6ce67abe01174be09ba2b5676c9ac2f4
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07423036B2

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