4-Methoxybenzohydrazide → HCID 178491626, 화합물
반응식
[Na].Cl.[C:3](=[NH:8])(OCC)[CH3:4].[CH3:9][O:10][C:11]1[CH:20]=[CH:19][C:14]([C:15]([NH:17][NH2:18])=[O:16])=[CH:13][CH:12]=1>C(O)C>[NH:8]=[C:3]([NH:18][NH:17][C:15](=[O:16])[C:14]1[CH:13]=[CH:12][C:11]([O:10][CH3:9])=[CH:20][CH:19]=1)[CH3:4]참가 물질
5
실험 절차
4.6 g (0.20 mol) sodium in 200 mL ethanol are combined at ambient temperature with a solution of 25 g (0.20 mol) ethyl acetimidate hydrochloride in 200 mL ethanol. The sodium chloride precipitated is suction filtered and 33.2 g (0.20 mol) 4-methoxybenzoic acid hydrazide are added to the filtrate. The reaction mixture is stirred overnight at ambient temperature and then cooled. The precipitate formed is separated off and washed with ethanol and diethyl ether. Yield: 33.6 g (81%); melting range=179-181° C.
후처리
- customThe sodium chloride precipitated
- filtrationfiltered
- temperaturecooled
- customThe precipitate formed
- customis separated off
- washwashed with ethanol and diethyl ether
출처 및 근거
- ORD 기록
- ord-6ce67abe01174be09ba2b5676c9ac2f4
- 출처 데이터셋
- uspto-grants-2008_09
- 특허 번호
- US07423036B2
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