4,6-Dichloro-2-methyl-5-nitropyrimidine → 4,6-Dichloro-2-methylpyrimidin-5-amine
반응식
[Cl:1][C:2]1[C:7]([N+:8]([O-])=O)=[C:6]([Cl:11])[N:5]=[C:4]([CH3:12])[N:3]=1>C1(C)C=CC=CC=1.[Ni]>[Cl:1][C:2]1[C:7]([NH2:8])=[C:6]([Cl:11])[N:5]=[C:4]([CH3:12])[N:3]=1참가 물질
4
실험 절차
The third intermediate, 4,6-dichloro-2-methyl-5-nitropyrimidine is hydrogenated over Raney-Ni as a 10% to 30% solution in toluene to afford the corresponding compound, 4,6-dichloro-2-methyl-5-aminopyrimidine, as a fourth intermediate.
출처 및 근거
- ORD 기록
- ord-fc482eaeb84f48f6beade7036825e8ec
- 출처 데이터셋
- uspto-grants-1998_03
- 특허 번호
- US05732717
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