Triethylamine → t-Butylpent-4-ynyloxy diphenyl silane

HRID 30585노트

반응식

HRID 30585 반응식
[C:1]([OH:6])#[C:2][CH2:3][CH2:4][CH3:5].[Si:7](Cl)([C:20]([CH3:23])([CH3:22])[CH3:21])([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.CCN(CC)CC.C([O-])([O-])=O.[K+].[K+]>C(Cl)Cl>[C:20]([Si:7]([O:6][CH2:1][CH2:2][CH2:3][C:4]#[CH:5])([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1)([CH3:23])([CH3:21])[CH3:22]

참가 물질

6

반응물 4

HCID 8471TriethylamineHCID 11430Potassium CarbonateHCID 94078tert-ButyldiphenylchlorosilaneHCID 10866258Pentynol

생성물 1

HCID 5461495t-Butylpent-4-ynyloxy diphenyl silane수율 98%

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

A mixture of pentynol (8.0 g, 95 mmol), t-butyldiphenylsilylchloride (28 g, 114 mmol) and Et3N (14 g, 138 mmol) in CH2Cl2 is stirred at room temperature for 16 h, treated with 1M K2CO3 and extracted with CH2Cl2. The combined extracts are dried over MgSO4 and concentrated in vacuo. The residue is purified by filtration on a silica pad to obtain 30 g of t-butylpent-4-ynyloxy diphenyl silane (yield: 98%

후처리

  1. extractionextracted with CH2Cl2
  2. dry with materialThe combined extracts are dried over MgSO4
  3. concentrationconcentrated in vacuo
  4. filtrationThe residue is purified by filtration on a silica pad

출처 및 근거

ORD 기록
ord-a4503c5eb7224d55b81763f390f48172
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07423158B2

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