Diglycolamine → N-(2-hydroxyethoxyethyl)hexahydrophthalimide

HRID 3068

반응식

HRID 3068 반응식
[NH2:1][CH2:2][CH2:3][O:4][CH2:5][CH2:6][OH:7].[C:8]1(=O)[O:13][C:11](=[O:12])[CH:10]2[CH2:14][CH2:15][CH2:16][CH2:17][CH:9]12>C(O)C>[OH:7][CH2:6][CH2:5][O:4][CH2:3][CH2:2][N:1]1[C:11](=[O:12])[CH:10]2[CH2:14][CH2:15][CH2:16][CH2:17][CH:9]2[C:8]1=[O:13]

참가 물질

4

반응물 2

HCID 13578DiglycolamineHCID 85689Hexahydrophthalic anhydride

생성물 1

HCID 55023972N-(2-hydroxyethoxyethyl)hexahydrophthalimide수율 96%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A 500-ml, two necked flask was equipped with a magnetic stirring bar, heating mantle and condenser. The flask was charged with 51 g of 2-(aminoethoxy) ethanol (0.49 mol.) and 250 ml of ethanol. Next, 75 g of hexahydrophthalic anhydride (0.49 mol.) was slowly added to the flask. After the addition was complete the reaction was refluxed for 12 hours. The IR spectrum indicated the reaction was complete. The ethanol was removed with a rotoevaporator to yield 113 g (96%) of N-(2-hydroxyethoxyethyl)hexahydrophthalimide.

후처리

  1. customA 500-ml, two necked flask was equipped with a magnetic stirring bar
  2. temperatureheating mantle and condenser
  3. additionAfter the addition
  4. temperaturewas refluxed for 12 hours
  5. customThe ethanol was removed with a rotoevaporator

출처 및 근거

ORD 기록
ord-0a1e984cbfd144cd8fa2cccd3f2e67f2
출처 데이터셋
uspto-grants-1998_03
특허 번호
US05733648

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