Benzylamine → 5-[1-(2,3-Difluorobenzyl)piperidin-4-ylmethoxy]quinazoline-2,4-diamine

HRID 307249

반응식

HRID 307249 반응식
[F:29][c:30]1[c:31]([CH2:32][Br:33])[cH:34][cH:35][cH:36][c:37]1[F:38].[NH2:1][CH2:2][c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1.[NH:9]1[CH2:10][CH2:11][CH:12]([CH2:15][O:16][c:17]2[c:18]3[c:19]([NH2:28])[n:20][c:21]([NH2:27])[n:22][c:23]3[cH:24][cH:25][cH:26]2)[CH2:13][CH2:14]1>>[N:9]1([CH2:32][c:31]2[c:30]([F:29])[c:37]([F:38])[cH:36][cH:35][cH:34]2)[CH2:10][CH2:11][CH:12]([CH2:15][O:16][c:17]2[c:18]3[c:19]([NH2:28])[n:20][c:21]([NH2:27])[n:22][c:23]3[cH:24][cH:25][cH:26]2)[CH2:13][CH2:14]1

참가 물질

4

반응물 3

HCID 7504BenzylamineHCID 5179841-(Bromomethyl)-2,3-difluoro-benzeneHCID 575765655-(Piperidin-4-ylmethoxy)quinazoline-2,4-diamine

생성물 1

HCID 250077865-[1-(2,3-Difluorobenzyl)piperidin-4-ylmethoxy]quinazoline-2,4-diamine

출처 및 근거

ORD 기록
ord-ed1e17e624b947b78503b254cc6201d9
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

연결된 노트

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