Hydrochloric Acid → 5-[4-fluoro-3-(2-methyl-2H-[1,2,4]triazol-3-ylmethoxy)phenyl]-2-trifluoromethyl-[1,8]naphthyridine

반응식

[Cl:24][CH2:25][c:26]1[n:27][cH:28][n:29][n:30]1[CH3:31].[ClH:23].[F:1][c:2]1[c:3]([OH:22])[cH:4][c:5](-[c:8]2[cH:9][cH:10][n:11][c:12]3[n:13][c:14]([C:18]([F:19])([F:20])[F:21])[cH:15][cH:16][c:17]23)[cH:6][cH:7]1>>[F:1][c:2]1[c:3]([O:22][CH2:25][c:26]2[n:27][cH:28][n:29][n:30]2[CH3:31])[cH:4][c:5](-[c:8]2[cH:9][cH:10][n:11][c:12]3[n:13][c:14]([C:18]([F:19])([F:20])[F:21])[cH:15][cH:16][c:17]23)[cH:6][cH:7]1

참가 물질

반응물 3

HCID 313Hydrochloric Acid

HCID 104192195-(Chloromethyl)-1-methyl-1H-1,2,4-triazole

HCID 222853142-Fluoro-5-(7-trifluoromethyl[1,8]naphthyridin-4-yl)phenol

생성물 1

HCID 101357735-[4-fluoro-3-(2-methyl-2H-[1,2,4]triazol-3-ylmethoxy)phenyl]-2-trifluoromethyl-[1,8]naphthyridine

출처 및 근거

ORD 기록: ord-77aa3fbe129246fb82535d65a4175d17
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

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