Palladium → 4-(5-Pyrimidin-2-yl-thiazol-2-yl)-piperazine-1-carboxylic acid tert-butyl ester

HRID 312030

반응식

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[s:15][c:16]([Br:19])[cH:17][n:18]2)[CH2:12][CH2:13]1.[C:41]([PH:42][C:43]([CH3:44])([CH3:45])[CH3:46])([CH3:47])([CH3:48])[CH3:49].[CH2:20]([Sn:21]([CH2:22][CH2:23][CH2:24][CH3:31])([c:25]1[n:26][cH:27][cH:28][cH:29][n:30]1)[CH2:32][CH2:33][CH2:34][CH3:35])[CH2:36][CH2:37][CH3:38].[Cs+:40].[F-:39].[Pd:50]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[s:15][c:16](-[c:25]3[n:26][cH:27][cH:28][cH:29][n:30]3)[cH:17][n:18]2)[CH2:12][CH2:13]1