Bicarbonate Ion → Tert-butyl 4-[4-[5-(2-fluoro-6-formylphenyl)-4,5-dihydro-1,2-oxazol-3-yl]-1,3-thiazol-2-yl]piperidine-1-carboxylate

HRID 312478노트

반응식

[C:41](=[O:42])([O-:43])[OH:44].[CH3:46][CH2:47][O:48][C:49](=[O:50])[CH3:51].[Cl:22][N:23]1[C:24](=[O:25])[CH2:26][CH2:27][C:28]1=[O:29].[F:30][c:31]1[c:32]([CH:39]=[CH2:40])[c:33]([CH:34]=[O:35])[cH:36][cH:37][cH:38]1.[K+:45].[OH2:52].[OH:1][N:2]=[CH:3][c:4]1[n:5][c:6]([CH:9]2[CH2:10][CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]2)[s:7][cH:8]1>>[O:1]1[N:2]=[C:3]([c:4]2[n:5][c:6]([CH:9]3[CH2:10][CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]3)[s:7][cH:8]2)[CH2:40][CH:39]1[c:32]1[c:31]([F:30])[cH:38][cH:37][cH:36][c:33]1[CH:34]=[O:35]