Chloroform → 3-[4-[4-(1,2,3,4-Tetrahydroisoquinolin-7-yloxymethyl)piperidin-1-yl]pyridin-3-yl]-2-propenoic acid ethyl ester

반응식

[CH2:1]([CH3:2])[O:3][C:4]([CH:5]=[CH:6][c:7]1[cH:8][n:9][cH:10][cH:11][c:12]1[N:13]1[CH2:14][CH2:15][CH:16]([CH2:19][O:20][c:21]2[cH:22][cH:23][c:24]3[c:29]([cH:30]2)[CH2:28][N:27]([C:31]([O:32][C:33]([CH3:34])([CH3:35])[CH3:36])=[O:37])[CH2:26][CH2:25]3)[CH2:17][CH2:18]1)=[O:38].[CH:46]([Cl:47])([Cl:48])[Cl:49].[OH:39][C:40]([C:41]([F:42])([F:43])[F:44])=[O:45]>>[CH2:1]([CH3:2])[O:3][C:4]([CH:5]=[CH:6][c:7]1[cH:8][n:9][cH:10][cH:11][c:12]1[N:13]1[CH2:14][CH2:15][CH:16]([CH2:19][O:20][c:21]2[cH:22][cH:23][c:24]3[c:29]([cH:30]2)[CH2:28][NH:27][CH2:26][CH2:25]3)[CH2:17][CH2:18]1)=[O:38]