Dimethylformamide → 1-Acetoxy-2-butanone
반응식
Br[CH2:2][C:3](=[O:6])[CH2:4][CH3:5].[C:7]([O-:10])(=[O:9])[CH3:8].[K+].CN(C)C=O>O>[C:7]([O:10][CH2:2][C:3](=[O:6])[CH2:4][CH3:5])(=[O:9])[CH3:8]참가 물질
5
실험 절차
A mixture of 1-bromobutan-2-one (10 g, 66.2 mmol), potassium acetate (7.8 g, 79.4 mmol), and N,N-dimethylformamide (50 ml) was stirred at room temperature for 5 days. Water was added to the reaction mixture and extracted with diethyl ether twice. The organic layers were combined and washed with a saturated saline solution, dried over magnesium sulfate, and filtrated. The filtrate was concentrated under reduced pressure to obtain the title compound (8.24 g) in the form of a mixture with N,N-dimethylformamide.
후처리
- extractionextracted with diethyl ether twice
- washwashed with a saturated saline solution
- dry with materialdried over magnesium sulfate
- filtrationfiltrated
- concentrationThe filtrate was concentrated under reduced pressure
출처 및 근거
- ORD 기록
- ord-049619a60e2141dfa110ff7f51c64d80
- 출처 데이터셋
- uspto-grants-2008_09
- 특허 번호
- US07425634B2
반응 노트
불러오는 중…