1,3-Dichloroacetone → HCID 22009802, 화합물

HRID 322293노트

반응식

HRID 322293 반응식
[CH3:1][O:2][C:3]1[S:7][C:6]([C:8]([NH2:10])=[O:9])=[CH:5][CH:4]=1.[Cl:11][CH2:12][C:13]([CH2:15]Cl)=O>>[Cl:11][CH2:12][C:13]1[N:10]=[C:8]([C:6]2[S:7][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)[O:9][CH:15]=1

참가 물질

3

반응물 2

HCID 107931,3-DichloroacetoneHCID 593880HCID 593880, 화합물

생성물 1

HCID 22009802HCID 22009802, 화합물수율 1.2%

실험 절차

In substantially the same manner as in Reference Example 47, 5-methoxy-2-thiophenecarboxamide was allowed to react with 1,3-dichloroacetone to give 4-chloromethyl-2-(5-methoxy-2-thienyl)oxazole. The yield was 1.2%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 64-65° C.

출처 및 근거

ORD 기록
ord-8a1881c581e4486eaae0e49045d7c9a4
출처 데이터셋
uspto-grants-2001_04
특허 번호
US06211215B1

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