Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dicyclohexylamine → Dicyclohexylammonium 4-[2-cyano-5-(3-pyridylmethoxy)phenoxy]-4-(2-methylphenyl)butanoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dicyclohexylamine | HCID 7582 | — |
| 반응물 | 4-(2-Cyano-5-(3-pyridylmethoxy)phenoxy)-4-(2-methylphenyl)butanoic acid | HCID 22010149 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | Dicyclohexylammonium 4-[2-cyano-5-(3-pyridylmethoxy)phenoxy]-4-(2-methylphenyl)butanoate | HCID 22010329 | — |
반응 단계
A mixture of 4-[2-cyano-5-(3-pyridylmethoxy)-phenoxy]-4-(2-methylphenyl)butanoic acid, thought to be the (R)-enantiomer, (50 mg), dicyclohexylamine (0.5 mL) and diethyl ether (10 mL) is stirred at ambient temperature for 18 hours. The resulting precipitate is collected and washed with diethyl ether, to give dicyclohexylammonium 4-[2-cyano-5-(3-pyridylmethoxy)phenoxy]-4-(2-methylphenyl)butanoate, thought to be the (R)-enantiomer, (30 mg) in the form of a white solid, m.p. 92-93° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06211234B1 |
| 출처 데이터셋 | uspto-grants-2001_04 |
| ORD ID | ord-d77ef45c1c564a5cb061d24f48a0d56d |
| 출처 메모 | uspto-grants-2001_04 |