N-Iodosuccinimide → 2,6,7-Trichloro-3-iodoimidazo[1,2-A]pyridine

HRID 323561

반응식

HRID 323561 반응식
[Cl:1][C:2]1[N:3]=[C:4]2[CH:9]=[CH:8][C:7]([Cl:10])=[CH:6][N:5]2[C:11]=1[I:12].[Cl:13]C1N=C2C=C(Cl)C(Cl)=CN2C=1.C1C(=O)N(I)C(=O)C1>>[I:12][C:11]1[N:5]2[CH:6]=[C:7]([Cl:10])[C:8]([Cl:13])=[CH:9][C:4]2=[N:3][C:2]=1[Cl:1]

참가 물질

4

반응물 3

HCID 120273N-IodosuccinimideHCID 106805212,6,7-TRICHLOROIMIDAZO[1,2-A]PYRIDINEHCID 11141504Imidazo[1,2-a]pyridine, 2,6-dichloro-3-iodo-

생성물 1

HCID 108717332,6,7-Trichloro-3-iodoimidazo[1,2-A]pyridine수율 82%

실험 절차

Following the preparation of compound 19, compound 16 (1.7 g, 7.7 mmol) was treated with NIS to give 2.2 g (82%) of compound 25 as a white crystalline solid.

출처 및 근거

ORD 기록
ord-7b9cf3b95c324769abf4f727face5d90
출처 데이터셋
uspto-grants-2001_04
특허 번호
US06214801B1

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