Benzoyl chloride → HCID 53910362, 화합물

반응식

[NH2:1][CH2:2][CH2:3][C:4]1[N:5]=[CH:6][N:7]([CH2:9][CH2:10][CH2:11][NH:12][C:13]([CH2:22][CH3:23])([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH2:14][CH3:15])[CH:8]=1.[C:24](Cl)(=[O:31])[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[CH2:14]([C:13]([NH:12][CH2:11][CH2:10][CH2:9][N:7]1[CH:8]=[C:4]([CH2:3][CH2:2][NH:1][C:24](=[O:31])[C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[N:5]=[CH:6]1)([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[CH2:22][CH3:23])[CH3:15]

참가 물질

반응물 2

HCID 7412Benzoyl chloride

HCID 183495694-(2-Aminoethyl)-N-(1-ethyl-1-phenylpropyl)-1H-imidazole-1-propanamine

생성물 1

HCID 53910362HCID 53910362, 화합물

실험 절차

3-[4-(2-Aminoethyl)imidazol-1-yl]-N-(1-ethyl-1-phenylpropyl)propylamine (1.0 g) was reacted with benzoyl chloride (0.38 ml) in a similar manner to Example 55 to give N-(2-{1-[3-(1-ethyl-1-phenylpropylamino)propyl]imidazol-4-yl}ethyl)benzamide, as an oil.

출처 및 근거

ORD 기록: ord-43bb1a35243d4634b3c8f906ad457cf7
출처 데이터셋: uspto-grants-2001_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06215001B1

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