반응식
[CH2:1]([C:3]1[CH:4]=[CH:5][C:6]2[CH:16](C3C(=O)NC(=O)N(C4C=CN=C(NCC(NC5SC=C(CC(O)=O)N=5)=O)N=4)C=3)[C:11]3[N:12]=[C:13]([CH3:15])[O:14][C:10]=3[CH:9]=[CH:8][C:7]=2[CH:45]=1)[CH3:2].C(OC(=O)C)(=[O:48])C.C(Cl)(=O)C.C(OC(=O)CC)(=O)CC.C(Cl)(=O)CC.C(O)(=O)CC>C(O)(=O)C>[CH2:1]([C:3]1[CH:4]=[CH:5][C:6]2[C:16](=[O:48])[C:11]3[N:12]=[C:13]([CH3:15])[O:14][C:10]=3[CH2:9][CH2:8][C:7]=2[CH:45]=1)[CH3:2]참가 물질
8
반응물 6
HCID 1032Propionic Acid
HCID 6367Acetyl chloride
HCID 7918Acetic Anhydride
HCID 31263Propionic anhydride
HCID 62324Propionyl chloride
HCID 88151464(+/-)-2-[2-[[4-[5-(7-Ethyl-2-methyl-4H-benzo[5,6]cyclohepta[1,2-d]oxazol-4-yl)-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl]pyrimidin-2-yl]amino]acetylamino]-4-thiazoleacetic acid생성물 1
시약·촉매·용매 1
실험 절차
The subtitle compound was prepared from the product of step (v) (9.20 g) according to the method of example 1 step (v) using acetic anhydride (4.9 ml), acetyl chloride (7.2 ml) and acetic acid (47 ml) (instead of propionic anhydride, propionyl chloride, and propionic acid).
출처 및 근거
- ORD 기록
- ord-09c19d5085954a989903fd98bc0eeb5c
- 출처 데이터셋
- uspto-grants-2001_04
- 특허 번호
- US06218376B1
연결된 노트
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